Acknowledgements
I would like to express my utmost gratitude to my two sponsors for helping me attend the FSI program and for allowing me to have this life-changing experience. I would like to thank Brian Davidson for gifting me the 2019 Brian Davidson Health Sciences Scholarship as it allowed me to pay room and board to attend FSI. I would also like to thank Xcel Energy for funding my research as without them I could not have done this project.
I would also like to thank my mentors, Tyler Sherman from UNCO and Reba Zimmerle fro CSU, as they helped edit my project and answered all of my questions. They worked with my group everyday and ensured that all of us got the best experience we could out of the program.
Also, I want to thank all of the FSI Staff. I want to thank Lori K. Ball and Riley Moen for everything they did this year with the application process and running the program. All of the teachers, Andrew Roth, Mattew DeSelm, and Reba Zimmerle, taught amazing classes and were always ready to help. I want to thank the FSI interns, Ferrin, Eja, and Maya, for everything they did and for becoming some of our closest friends these past 6 weeks. And last, but not least, I want to thank our FSI RAs, Jaden and Michael, for offering their expertise on our projects and being the best RAs.
Finally, I want to thank my family and friends back home and all of my fellow FSI Scholars as we have all definitely grown close these past weeks and I could not have asked for a better summer.
I would also like to thank my mentors, Tyler Sherman from UNCO and Reba Zimmerle fro CSU, as they helped edit my project and answered all of my questions. They worked with my group everyday and ensured that all of us got the best experience we could out of the program.
Also, I want to thank all of the FSI Staff. I want to thank Lori K. Ball and Riley Moen for everything they did this year with the application process and running the program. All of the teachers, Andrew Roth, Mattew DeSelm, and Reba Zimmerle, taught amazing classes and were always ready to help. I want to thank the FSI interns, Ferrin, Eja, and Maya, for everything they did and for becoming some of our closest friends these past 6 weeks. And last, but not least, I want to thank our FSI RAs, Jaden and Michael, for offering their expertise on our projects and being the best RAs.
Finally, I want to thank my family and friends back home and all of my fellow FSI Scholars as we have all definitely grown close these past weeks and I could not have asked for a better summer.
References
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Zackular, J. P., Baxter, N. T., Iverson, K. D., Sadler, W. D., Petrosino, J. F., Chen, G. Y., & Schloss, P. D. (2013). The Gut Microbiome Modulates Colon Tumorigenesis. MBio, 4(6). doi:10.1128/mbio.00692-13
Cell Division and Cancer. (n.d.). Retrieved June 30, 2019, from https://www.nature.com/scitable/topicpage/cell-division-and-cancer-14046590
Churko, J. M., Mantalas, G. L., Snyder, M. P., & Wu, J. C. (2013). Overview of High Throughput Sequencing Technologies to Elucidate Molecular Pathways in Cardiovascular Diseases. Circulation Research, 112(12), 1613-1623. doi:10.1161/circresaha.113.300939
Fessler, J., Matson, V., & Gajewski, T. F. (2019). Exploring the emerging role of the microbiome in cancer immunotherapy. Journal for ImmunoTherapy of Cancer,7(1). doi:10.1186/s40425-019-0574-4
Geller, L. T., Barzily-Rokni, M., Danino, T., Jonas, O. H., Shental, N., Nejman, D., … Straussman, R. (2017). Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine. Science (New York, N.Y.), 357(6356), 1156–1160. doi:10.1126/science.aah5043
Grenier Davis, S. F. (2017). Characterization and manipulation of the colonic microbiome in a mouse model of colon cancer (Order No. 10687941). Available from ProQuest Dissertations & Theses Global. (1987953863). Retrieved from https://unco.idm.oclc.org/login?url=https://search.proquest.com/docview/1987953863?accountid=12832
Gut Microbiota Info. (n.d.). Retrieved June 30, 2019, from https://www.gutmicrobiotaforhealth.com/en/about-gut-microbiota-info/
Heintz-Buschart, A., & Wilmes, P. (2018). Human Gut Microbiome: Function Matters. Trends in Microbiology,26(7), 563-574. doi:10.1016/j.tim.2017.11.002
Koenig, J. E., Spor, A., Scalfone, N., Fricker, A. D., Stombaugh, J., Knight, R., . . . Klaenhammer, T. R. (2011). Succession of microbial consortia in the developing infant gut microbiome. Yearbook of Neonatal and Perinatal Medicine, 2011, 125-126. doi:10.1016/j.ynpm.2011.07.111
Levy, M., Kolodziejczyk, A. A., Thaiss, C. A., & Elinav, E. (2017). Dysbiosis and the immune system. Nature Reviews. Immunology, 17(4), 219-232. doi:http://dx.doi.org/10.1038/nri.2017.7
Lyte, M. (2014). Microbial Endocrinology and the Microbiota-Gut-Brain Axis. Advances in Experimental Medicine and Biology Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease,3-24. doi:10.1007/978-1-4939-0897-4_1
Matrana, M. R., & Ibrahim, N. K. (2011). Breast Cancer Metastasis to the Central Nervous System. Tumors of the Central Nervous System, Volume 4,35-49. doi:10.1007/978-94-007-1706-0_4
Montassier, E., Gastinne, T., Vangay, P., Al-Ghalith, G. A., Varannes, S. B., Massart, S., . . . Knights, D. (2015). Chemotherapy-driven dysbiosis in the intestinal microbiome. Alimentary Pharmacology & Therapeutics, 42(5), 515-528. doi:10.1111/apt.13302
Neu, J. (2011). Succession of microbial consortia in the developing infant gut microbiome. Yearbook of Neonatal and Perinatal Medicine, 2011, 125-126. doi:10.1016/j.ynpm.2011.07.111
Scientific, T. F. (n.d.). NanoDrop: How it works: Thermo Fisher Scientific - US. Retrieved July 11, 2019, from https://www.thermofisher.com
Scientific, T. F. (2014, May 19). Ion Torrent™ next-gen sequencing technology. Retrieved July 11, 2019, from https://www.youtube.com/watch?v=WYBzbxIfuKs
Side Effects of Radiation Therapy. (2019, January 08). Retrieved July 12, 2019, from https://www.cancer.net/navigating-cancer-care/how-cancer-treated/radiation-therapy/side-effects-radiation-therapy
The Tumor Microbiome. (n.d.). Retrieved June 25, 2019, from http://www.weizmann.ac.il/mcb/Straussman/research-activities/tumor-microbiome
Tian, Y., Li, M., Song, W., Jiang, R., & Li, Y. (2019). Effects of probiotics on chemotherapy in patients with lung cancer. Oncology Letters. doi:10.3892/ol.2019.9906
Types of Cancer Treatment. (n.d.). Retrieved June 30, 2019, from https://www.cancer.gov/about-cancer/treatment/types
Vivarelli, S., Salemi, R., Candido, S., Falzone, L., Santagati, M., Stefani, S., … Libra, M. (2019). Gut Microbiota and Cancer: From Pathogenesis to Therapy. Cancers, 11(1), 38. doi:10.3390/cancers11010038
What Is Cancer? (n.d.). Retrieved June 30, 2019, from https://www.cancer.gov/about-cancer/understanding/what-is-cancer
Yang, Y., Wei, Q., Ma, Y., & Qin, H. (2016). Abstract CT155: The effect of perioperative probiotics treatment for colorectal cancer: Short-term outcomes of a randomized controlled trial. Clinical Trials. doi:10.1158/1538-7445.am2016-ct155
Zackular, J. P., Baxter, N. T., Iverson, K. D., Sadler, W. D., Petrosino, J. F., Chen, G. Y., & Schloss, P. D. (2013). The Gut Microbiome Modulates Colon Tumorigenesis. MBio, 4(6). doi:10.1128/mbio.00692-13